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Intermittent microinjection method in freely-moving rats and its application to neuropharmacology
1Behavioral Neuroscience Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA. sikemoto@intra.nida.nih.gov
Abstract:
Intermittent delivery of drugs into a discrete brain region has proven to be a useful technique. Described here is a micro-pump injection unit with miniature step-motors. This injection system is reliable, easy to operate and inexpensive to construct. The application of intermittent injection systems to study reward neurochemical circuits is discussed.