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Related Experiment Videos

Pediatric genitourinary tumors.

Paul A Merguerian1

  • 1Department of Pediatric Urology, Children's Hospital Central California, 9300 Valley Children's Place, Madera, CA 93638, USA.

Current Opinion in Oncology
|June 5, 2003
PubMed
Summary
This summary is machine-generated.

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Pediatric genitourinary tumors are advancing in treatment and evaluation. Research is identifying molecular markers to tailor intensified treatment for aggressive childhood cancers.

Area of Science:

  • Pediatric Oncology
  • Genitourinary Oncology
  • Molecular Biology

Background:

  • Pediatric genitourinary tumors require ongoing research for improved management.
  • Tumorigenesis research is rapidly evolving at cellular, molecular, and genetic levels.

Purpose of the Study:

  • To review the 2002 literature on pediatric genitourinary tumors.
  • To highlight advances in the evaluation and treatment of these cancers.

Main Methods:

  • Literature review of scientific publications from 2002.
  • Analysis of research on cellular, molecular, and genetic aspects of tumorigenesis.

Main Results:

  • Molecular and cellular biology research is identifying prognostic markers.

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  • These markers may predict a worse prognosis in pediatric genitourinary tumors.

    • Conclusions:

    • Identification of prognostic markers enables a more tailored treatment approach.
    • Intensified treatment strategies can be developed for aggressive pediatric tumors.