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Updated: Sep 25, 2026
Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
Published on: April 7, 2023
[Protective effect of daizein on apoptosis cells of nasal mucosas in ovariectomized rats]
Ben-ming Qi1, Xing-hua Tian, Ji-bao Wang
1Department of Otorhinolaryngology, First People's Hospital of Yunnan Province, Kunming 650001, China. qibenming@21cn.com
Objective:
To study the protective effect of daizein on apoptosis cells of atrophic nasal mucosas in ovariectomized rats.
Methods:
Sixty rats were divided into four groups as contrary, ovariectomized, ovariectomized + nylestriol (O + N) and ovariectomized + daizein (O + D), each with 15 rats. Earlier apotosis cells of nasal mucosas taken from nasal septum were measured with flow cytometry.
Results:
Compared with contrary group, the number of apoptosis cells of mucosas increased after being ovariectomized, the number of apoptosis cells of mucosas in O + N and O + D groups didn't change.
Conclusion:
Estrogen replacement and daizein might have effects on protecting cells of mucosas from lacking of estrogen by decreasing apoptosis cells in ovariectomized rats.