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Metallic stenting for treatment of central venous obstruction in hemodialysis patients
Chiung-Yu Chen1, Huei-Lung Liang, Huay-Ban Pan
1Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
Insights
Primary Wallstent placement offers a safe and technically successful option for treating central venous obstructions in hemodialysis patients. While it provides extended access, repeated interventions may be needed to maintain patency.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Nephrology
Background:
- Central venous obstruction is a frequent and severe complication in patients undergoing hemodialysis.
- Recurrence rates are high after balloon dilation, and surgical repair poses significant risks for these patients.
Purpose of the Study:
- To assess the efficacy of primary Wallstent placement in managing hemodialysis-related central venous obstructions.
Main Methods:
- Eighteen hemodialysis patients with symptomatic central venous obstructions underwent primary Wallstent placement.
- Technical success, complications, and patency rates (primary and secondary) were evaluated using survival analysis.
Main Results:
- 100% technical success was achieved with Wallstent deployment in 18 patients (25 stents).
- Re-obstruction occurred in 14 instances, managed with angioplasty or additional stenting; no stent migration was observed.
- Primary patency rates at 18 months were 16% for the stent and 0% for access, while secondary patency rates at 24 months reached 68-72%.
Conclusions:
- Wallstents are safe and achieve high technical success for hemodialysis-related central venous obstructions.
- Wallstent placement ensures prolonged hemodialysis access, though repeat interventions may be required.
- This approach offers a viable solution for managing complex venous obstructions in hemodialysis patients.
Background:
Central venous obstruction is a serious and common complication in hemodialysis patients. The recurrence rate is high after balloon dilation, while surgical repair is hazardous in these chronically ill patients. The aim of this study was to evaluate the efficacy of primary Wallstent placement for treatment of hemodialysis-related central venous obstructions.
Methods:
Eighteen hemodialysis patients with symptomatic shunt dysfunction and arm swelling due to subclavian (n = 3) or innominate (n = 15) venous obstructions were treated at Kaohsiung Veterans General Hospital with primary Wallstent placement from November 1998 to August 2001. Technical success and complications were reported. Primary and secondary patency rates of stent and hemodialysis access were calculated by survival analysis with Kaplan-Meier method.
Results:
A total of twenty-five Wallstents were deployed for central venous stenosis (n = 18) and occlusion (n = 7) in these 18 hemodialysis patients. The initial technical success rate was 100%. Fourteen episodes of re-obstruction developed during the observation period. Of them, seven episodes occurred within the stent, four episodes outside of but abutting to the peripheral end of the stent, and another three episodes of re-obstruction were attributed to delayed shortening of the Wallstent. Six of the 14 episodes were treated percutaneously with angioplasty alone, while seven episodes necessitated additional stent placement. No stent migration or other complications were encountered. Primary patency rates of stent and hemodialysis access at 3, 6, 12 and 18 months were 100 and 89%, 73 and 68%, 49 and 42%, and 16 and 0%, respectively. Secondary patency rates of stent and hemodialysis access each were both 100% after 3 months, 93 and 100% after 6 months, 85 and 91% after 12 months and, 68 and 72% after 24 months.
Conclusions:
Wallstents are safe to deploy, with excellent technical success for hemodialysis-related central venous obstructions. The Wallstent provides continued use of a hemodialysis access for a substantial period. However, repeated interventions may be necessary to maintain the patency.
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