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E1AF expression levels are not associated with prognosis in human breast cancer
Paul N Span1, Peggy Manders, Joop J T M Heuvel
1Department of Chemical Endocrinology, University Medical Center Nijmegen, Nijmegen, The Netherlands. p.span@ace.umcn.nl
Breast Cancer Research and Treatment
|June 5, 2003
Abstract:
E1AF is a transcription factor involved in regulation of several metastasis-associated genes, and is associated with overexpression of HER2/neu. We were unable to find a clear prognostic value of E1AF expression in human breast cancer. Furthermore, no association of E1AF levels with HER2/neu mRNA levels, hormone receptor status, histological grade, tumor size, or lymph node involvement was found.