Cell brain: a new focus in the postgenomic era

The centrosome, together with the embedded centrioles and connecting filaments, has come to be regarded as the 'brain' of a cell, analogous to the long known brain of an animal or a human being. It is through the 'brain' that different cellular activities are coordinated as a whole. In this article, comparative studies of the principles of life at varying levels and of the new roles of different cellular organelles in maintaining a healthy life for an organism provide further support to this theory, which is discussed based on the latest findings. Hopefully, this new theory can make a great contribution to break the paradigm of nucleus (or genes) as causes of all problems.