Antibacterial activity of Pulicaria dysenterica extracts
1Pharmacognosy Department, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, PO Box 14155-6153, Tehran, Iran. bnickavar@yahoo.com
Abstract:
Aqueous, methanolic and chloroformic extracts of Pulicaria dysenterica aerial parts were tested for their antibacterial activity using the disc-diffusion assay technique. The methanolic extract was found to be the most effective extract against three out of six tested bacteria. All of the extracts were active against Vibrio cholera.
Insights
The methanolic extract of Pulicaria dysenterica aerial parts showed the most potent antibacterial activity against several bacteria. All tested extracts demonstrated effectiveness against Vibrio cholera.
Area of Science:
- Phytochemistry
- Microbiology
- Pharmacology
Background:
- Pulicaria dysenterica is a plant species with potential medicinal properties.
- Investigating the antibacterial potential of plant extracts is crucial for discovering new antimicrobial agents.
Purpose of the Study:
- To evaluate the antibacterial activity of different extracts from Pulicaria dysenterica aerial parts.
- To identify the most effective extract against a panel of bacteria, including Vibrio cholera.
Main Methods:
- Preparation of aqueous, methanolic, and chloroformic extracts from Pulicaria dysenterica aerial parts.
- Antibacterial activity assessment using the disc-diffusion assay technique.
- Testing against six different bacterial strains, including Vibrio cholera.
Main Results:
- The methanolic extract exhibited the strongest antibacterial effect against three of the six tested bacteria.
- All tested extracts, including aqueous and chloroformic, displayed activity against Vibrio cholera.
Conclusions:
- Pulicaria dysenterica possesses significant antibacterial properties, particularly its methanolic extract.
- The plant's extracts show promise as a natural source for combating bacterial infections, notably Vibrio cholera.
