Related Experiment Video
Updated: Sep 25, 2026
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Morphological study of corneal endothelium and corneal thickness in pseudoexfoliation syndrome
Kenji Inoue1, Kazuko Okugawa, Tetsuro Oshika
1Department of Ophthalmology, Nadogaya Hospital, Chiba, Japan.
Purpose:
To examine the endothelial morphology and the central thickness of the cornea in the eyes of patients with pseudoexfoliation syndrome (PXS).
Methods:
The corneal endothelium was investigated in 21 patients (26 PXS eyes; 7 eyes of glaucoma patients, and 19 eyes of patients without glaucoma) and in 30 patients with senile cataract or refractive errors who served as the control group (30 non-PXS eyes). The corneal endothelial morphology and central corneal thickness (CCT) were compared between the two groups.
Results:
The corneal endothelial cell density was significantly lower in the PXS eyes (2336+/-383 cells/mm(2)) than in the non-PXS eyes (2632+/-327 cells/mm(2)) (P=.003). There was no significant difference in the coefficient of variation for the cell area and the percentage of hexagonal cells between these two groups. The central cornea was significantly thinner in the PXS eyes (529+/-31 micro m) than in the non-PXS eyes (547+/-28 micro m) (P=.03). There were no significant differences in these factors between the PXS eyes in patients with and without glaucoma.
Conclusions:
In PXS eyes, regardless of the presence of glaucoma in the patients, the corneal endothelial cell density is decreased and the central cornea is thin.
More Related Videos
07:51Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
12:36A Human Corneal Organ Culture Model of Descemet's Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
Published on: July 22, 2022