Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression

Exchange dynamics and kinetic control of gene regulation complexes.

Nature reviews. Molecular cell biology·2026

Elevated MyoD1 levels expand genome-wide binding and the repertoire of regulated genes.

Proceedings of the National Academy of Sciences of the United States of America·2026

Unstructured transcription factor interactions enable emergent specificity.

Science (New York, N.Y.)·2026

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.

Cell reports·2026

Modulating MyoD1 dosage activates alternate cell fate beyond myogenic differentiation.

bioRxiv : the preprint server for biology·2025

Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes.

Molecular cell·2025

Differential control of both cell cycle-regulated and quantitative histone mRNA expression by Drosophila Mute.

Genes & development·2026

Temporal gating dictates stress-induced transcript export from the nucleus.

Genes & development·2026

rRNA 5'ETS processing contributes to nucleolar organization and nuclear architecture.

Genes & development·2026

Multimerization of ELAV in Drosophila is essential for directing neuronal alternative splicing and polyadenylation programs.

Genes & development·2026

mTOR inactivation governs adaptive survival to ribosome biogenesis deficiency.

Genes & development·2026

Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities.

Genes & development·2026

Clinical and Molecular Findings in Two Siblings with a Novel Homozygous DCAF17 Frameshift Variant and Review of the Literature: A Case Report.

Molecular syndromology·2026

Integrative methylome and transcriptome analysis reveals genotype and sequence context-specific responses to aluminum stress in rice.

Frontiers in plant science·2026

AdaBoost-based differential diagnosis of gouty arthritis and rheumatoid arthritis: model construction, temporal validation, and SHAP visualization.

Frontiers in medicine·2026

Refining genetic discoveries of group knockoffs via a feature-level filter.

Journal of the Royal Statistical Society. Series C, Applied statistics·2026

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

Medicine·2026

Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study.

Medicine·2026

Related Experiment Videos

Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression

Related Concept Videos

Exchange dynamics and kinetic control of gene regulation complexes.

Elevated MyoD1 levels expand genome-wide binding and the repertoire of regulated genes.

Unstructured transcription factor interactions enable emergent specificity.

FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity.

Modulating MyoD1 dosage activates alternate cell fate beyond myogenic differentiation.

Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes.

Differential control of both cell cycle-regulated and quantitative histone mRNA expression by Drosophila Mute.

Temporal gating dictates stress-induced transcript export from the nucleus.

rRNA 5'ETS processing contributes to nucleolar organization and nuclear architecture.

Multimerization of ELAV in Drosophila is essential for directing neuronal alternative splicing and polyadenylation programs.

mTOR inactivation governs adaptive survival to ribosome biogenesis deficiency.

Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities.

Clinical and Molecular Findings in Two Siblings with a Novel Homozygous DCAF17 Frameshift Variant and Review of the Literature: A Case Report.

Integrative methylome and transcriptome analysis reveals genotype and sequence context-specific responses to aluminum stress in rice.

AdaBoost-based differential diagnosis of gouty arthritis and rheumatoid arthritis: model construction, temporal validation, and SHAP visualization.

Refining genetic discoveries of group knockoffs via a feature-level filter.

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study.

Related Experiment Videos

Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression

Related Concept Videos

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