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Published on: December 21, 2019
CT for thromboembolic disease
Lacey Washington1, Meltem Gulsun
1Department of Radiology, Medical College of Wisconsin, Milwaukee, 53226-3596, USA. lwash@mcw.edu
Insights
Pulmonary embolism (PE) and deep venous thrombosis (DVT) are part of venous thromboembolic disease (VTE). CT pulmonary arteriography (CTPA) and computed tomography venography (CTV) offer a single noninvasive test to diagnose both PE and DVT.
Area of Science:
- Radiology
- Cardiovascular Medicine
- Diagnostic Imaging
Background:
- Pulmonary embolism (PE) and deep venous thrombosis (DVT) are manifestations of venous thromboembolic disease (VTE).
- VTE is frequently underestimated, underdiagnosed, and undertreated.
- Accurate diagnosis is crucial for effective management.
Purpose of the Study:
- To review the epidemiology of VTE.
- To outline the diagnostic algorithm for suspected VTE.
- To detail CT pulmonary arteriography (CTPA) and computed tomography venography (CTV) protocols and interpretation.
Main Methods:
- Review of existing literature on VTE epidemiology and diagnosis.
- Description of CTPA and CTV techniques.
- Discussion of image interpretation challenges.
Main Results:
- CTPA combined with CTV provides a single noninvasive method for evaluating both PE and DVT.
- The review covers diagnostic algorithms and specific imaging protocols.
- Challenges in interpreting CTPA for radiologists are highlighted.
Conclusions:
- CTPA and CTV represent a significant advancement in the noninvasive diagnosis of VTE.
- Standardized protocols and interpretation guidelines are essential for optimal use.
- Improved diagnostic capabilities may lead to better VTE management.
Abstract:
Pulmonary embolism (PE) and deep venous thrombosis (DVT) constitute the two clinical manifestations of venous thromboembolic disease (VTE). The recent innovation of computed tomography venography (CTV) in conjunction with CT pulmonary arteriography (CTPA) provides a single noninvasive diagnostic test that can evaluate both components of VTE. PE is often an underestimated, underdiagnosed, and, consequently, undertreated disease entity. Herein, we review the epidemiology of thromboembolic disease, the diagnostic algorithm used in evaluation of patients with suspected VTE, and protocols for performing CTPA and CTV. Interpretation of these examinations is discussed in detail, because CTPA may pose new challenges to the practicing radiologist.
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