CT for thromboembolic disease

Lacey Washington1, Meltem Gulsun

  • 1Department of Radiology, Medical College of Wisconsin, Milwaukee, 53226-3596, USA. lwash@mcw.edu

Insights

Pulmonary embolism (PE) and deep venous thrombosis (DVT) are part of venous thromboembolic disease (VTE). CT pulmonary arteriography (CTPA) and computed tomography venography (CTV) offer a single noninvasive test to diagnose both PE and DVT.

Area of Science:

  • Radiology
  • Cardiovascular Medicine
  • Diagnostic Imaging

Background:

  • Pulmonary embolism (PE) and deep venous thrombosis (DVT) are manifestations of venous thromboembolic disease (VTE).
  • VTE is frequently underestimated, underdiagnosed, and undertreated.
  • Accurate diagnosis is crucial for effective management.

Purpose of the Study:

  • To review the epidemiology of VTE.
  • To outline the diagnostic algorithm for suspected VTE.
  • To detail CT pulmonary arteriography (CTPA) and computed tomography venography (CTV) protocols and interpretation.

Main Methods:

  • Review of existing literature on VTE epidemiology and diagnosis.
  • Description of CTPA and CTV techniques.
  • Discussion of image interpretation challenges.

Main Results:

  • CTPA combined with CTV provides a single noninvasive method for evaluating both PE and DVT.
  • The review covers diagnostic algorithms and specific imaging protocols.
  • Challenges in interpreting CTPA for radiologists are highlighted.

Conclusions:

  • CTPA and CTV represent a significant advancement in the noninvasive diagnosis of VTE.
  • Standardized protocols and interpretation guidelines are essential for optimal use.
  • Improved diagnostic capabilities may lead to better VTE management.

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