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Pit pattern analysis by magnifying chromoendoscopy for the diagnosis of colorectal polyps
Hui-Hsiung Liu1, Shin-Ei Kudo, Jyh-Pyng Juch
1Graduate Institute of Public Health, Taipei Medical University, Taipei, Taiwan.
Background And Purpose:
The development of magnifying chromoendoscopy has facilitated the observation of mucosal pit patterns. This study investigated the value of this technology in predicting the histologic findings of colorectal lesions.
Methods:
A total of 954 colorectal polyps were included. After identifying the lesions at colonoscopy, 0.2% indigocarmine solution was sprayed and then the zoom apparatus was switched to make a magnified view of the stained crypt orifice at a maximum 100 times magnification. The observed pit patterns were classified into 6 categories (I, II, IIIL, IIIS, IV, and V) according to Kudo's classification. Type I and II were designated as non-neoplastic patterns whereas other types were neoplastic. Correlation of the pit pattern with the findings of histologic examinations of resected or biopsied polyps was performed.
Results:
There were 678 diminutive (
Conclusions:
Characteristic pit patterns obtained by magnifying chromoendoscopy provide useful clues for differentiation of adenomatous from non-adenomatous polyps. Used appropriately in experienced hands, this technique offers a valuable adjunct to standard colonoscopy in predicting the histologic characteristics of colorectal polyps.