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Related Experiment Videos

Intravascular lymphomatosis.

P C W Lui1, G K C Wong, W S Poon

  • 1Department of Pathology, United Christian Hospital, Hong Kong.

Journal of Clinical Pathology
|June 5, 2003
PubMed
Summary
This summary is machine-generated.

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Intravascular lymphomatosis (IVL) is a rare lymphoma causing vascular occlusion. This case highlights IVL presenting with disseminated intravascular coagulation and intracerebral hemorrhage, a rare but severe complication.

Area of Science:

  • Oncology
  • Hematology
  • Pathology

Background:

  • Intravascular lymphomatosis (IVL) is an uncommon angiotropic large cell lymphoma.
  • It primarily affects blood vessels, leading to occlusion.
  • Predominantly B-cell in origin, it can also be T-cell or Ki-1 type.

Observation:

  • The central nervous system and skin are most frequently involved organs.
  • Common presentations include encephalopathy, neurological deficits, and skin lesions.
  • Other affected organs: adrenals, lungs, heart, spleen, liver, pancreas, kidneys, and genital tract.
  • Fever of unknown origin is a frequent clinical sign.

Findings:

  • Bone marrow, blood, cerebrospinal fluid, and lymph nodes are typically spared in IVL.

Related Experiment Videos

  • Disseminated intravascular coagulation (DIC) and anasarca are rare presentations.
  • This report details a postmortem case of IVL with initial presentation of DIC complicated by intracerebral hemorrhage.

    • Implications:

    • This case expands the understanding of rare IVL presentations, particularly DIC.
    • Highlights the importance of considering IVL in patients with unexplained coagulopathy and neurological symptoms.
    • Emphasizes the diagnostic challenges and potential severity of intravascular lymphomatosis.