Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

WATER RELATIONS OF MYCORRHIZAL AND PHOSPHORUS-FERTILIZED NON-MYCORRHIZAL CITRUS UNDER DROUGHT STRESS.

The New phytologist·2021
Same author

The Influence of Spray Adjuvants on Exacerbation of Citrus Bacterial Spot.

Plant disease·2019
Same author

Metalaxyl-Resistant Isolates of Phytophthora nicotianae: Occurrence, Sensitivity, and Competitive Parasitic Ability on Citrus.

Plant disease·2019
Same author

Composted Municipal Waste Reduces Infection of Citrus Seedlings by Phytophthora nicotianae.

Plant disease·2019
Same author

Phytophthora Brown Rot of Citrus: Temperature and Moisture Effects on Infection, Sporangium Production, and Dispersal.

Plant disease·2019
Same author

Lack of Control of Citrus Canker by Induced Systemic Resistance Compounds.

Plant disease·2019

Related Experiment Video

Updated: May 12, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
06:35

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

Published on: June 28, 2021

Tumor-induced acute pancreatitis.

D G Niccolini, J H Graham, P A Banks

    Gastroenterology
    |July 1, 1976
    PubMed
    Summary

    Pancreatic cancer can cause acute pancreatitis, leading to pseudocysts and ascites. This case highlights bronchogenic carcinoma metastasis to the pancreas, causing duct rupture and obstruction.

    Area of Science:

    • Oncology
    • Gastroenterology
    • Pathology

    Background:

    • Pancreatic neoplasms and metastatic tumors can induce acute pancreatitis.
    • Pancreatic pseudocysts and ascites are known complications of severe pancreatitis.

    Observation:

    • This report details a case of bronchogenic carcinoma metastasizing to the pancreas.
    • The metastasis initiated an episode of acute pancreatitis.

    Findings:

    • Histological examination revealed tumor cells rupturing pancreatic ducts.
    • Tumor nests obstructed pancreatic ducts, contributing to pancreatitis.

    Implications:

    • Metastatic pancreatic tumors, including lung cancer, should be considered in acute pancreatitis cases.

    More Related Videos

    A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
    06:44

    A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

    Published on: February 28, 2021

    Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
    07:10

    Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

    Published on: April 1, 2022

    Related Experiment Videos

    Last Updated: May 12, 2026

    Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
    06:35

    Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

    Published on: June 28, 2021

    A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
    06:44

    A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

    Published on: February 28, 2021

    Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
    07:10

    Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct

    Published on: April 1, 2022

  • Understanding tumor-duct interactions is crucial for diagnosing and managing pancreatic complications.