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Updated: Aug 13, 2026

Mapping Molecular Diffusion in the Plasma Membrane by Multiple-Target Tracing (MTT)
Published on: May 27, 2012
Diffusion dynamics, moments, and distribution of first-passage time on the protein-folding energy landscape, with
Chi-Lun Lee1, Chien-Ting Lin, George Stell
1Department of Physics, State University of New York at Stony Brook, 11794, USA.
Abstract:
We study the dynamics of protein folding via statistical energy-landscape theory. In particular, we concentrate on the local-connectivity case with the folding progress described by the fraction of native conformations. We found that the first passage-time (FPT) distribution undergoes a dynamic transition at a temperature below which the FPT distribution develops a power-law tail, a signature of the intermittent nonexponential kinetic phenomena for the folding dynamics. Possible applications to single-molecule dynamics experiments are discussed.
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