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Polymorphism of 17 STRs by multiplex analysis in Japanese population
M Hashiyada1, Y Itakura, T Nagashima
1Department of Public Health and Forensic Medicine, Division of Forensic Medicine, Tohoku University Graduate School of Medicine, Seiryo-machi 2-1, Aoba-ku, Sendai 980-8575, Japan. hashiyad@forensic.med.tohoku.ac.jp
Forensic Science International
|June 6, 2003
Summary
Genetic analysis of 17 short tandem repeat (STR) loci was performed on 526 Japanese individuals. This study provides essential allele frequency data for forensic and population genetics applications in Japan.
Area of Science:
- Forensic Genetics
- Population Genetics
- Human Genetics
Background:
- Short tandem repeats (STRs) are highly polymorphic DNA markers crucial for human identification.
- Understanding allele frequencies in specific populations is vital for accurate forensic analysis and genetic research.
Purpose of the Study:
- To determine the genotype and allele frequency distribution of 17 STR loci in a Japanese population.
- To establish a genetic profile database for the Japanese population.
Main Methods:
- DNA samples from 526 unrelated Japanese individuals were analyzed.
- The PowerPlex 16 system and AmpFlSTR Identifiler kits were utilized for STR typing.
Main Results:
- Allele frequencies for 17 STR loci were calculated.
- Genotypic data were obtained for the studied Japanese cohort.
Conclusions:
- The generated STR allele frequency data contribute to forensic science and population genetics in Japan.
- This dataset serves as a valuable resource for genetic identification and anthropological studies within the Japanese population.