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An appraisal of different cardiac risk reduction strategies in vascular surgery patients
J D Kakisis1, F Abir, C D Liapis
1Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT 06510, U.S.A.
Insights
Beta-blockers effectively reduce cardiac risk in vascular surgery patients, with strong evidence for high-risk individuals. Coronary revascularization is generally not recommended solely for perioperative benefit.
Area of Science:
- Cardiology
- Vascular Surgery
- Perioperative Medicine
Background:
- Patients undergoing vascular surgery face significant cardiac risks.
- Prophylactic cardiac interventions aim to mitigate these perioperative risks.
Purpose of the Study:
- To review evidence on cardiac risk reduction strategies in vascular surgery.
- To assess the benefits and risks of interventional and medical approaches.
Main Methods:
- Critical literature review of studies on prophylactic cardiac maneuvers.
- Outcome measures included overall mortality, cardiac mortality, and myocardial infarction rates.
Main Results:
- Coronary artery bypass grafting decreased perioperative mortality by 60% but often doesn't outweigh combined risks.
- Percutaneous transluminal angioplasty shows insufficient evidence for cardioprotection.
- Beta-blockade significantly reduces perioperative mortality and cardiac morbidity in both high- and low-risk patients.
Conclusions:
- Coronary revascularization is rarely indicated solely for vascular surgery and should be reserved for patients with independent cardiac need.
- Only beta-blockers have demonstrated efficacy in reducing cardiac risk associated with vascular surgery.
Objectives:
to summarize existing evidence regarding the benefits and the risks of all available interventional and medical means aimed at cardiac risk reduction in patients undergoing vascular surgery.
Design:
review of the literature.
Materials And Methods:
a critical review of all studies examining the impact of various prophylactic cardiac maneuvers on perioperative outcome following vascular surgery was performed. Overall mortality, cardiac mortality and myocardial infarction rate were used as the outcome measures.
Results:
coronary artery bypass grafting is associated with a 60% decrease in perioperative mortality in patients undergoing vascular surgery, but in most of the cases this decrease does not outweigh the combined risk of the cardiac and the subsequent noncardiac vascular procedure. Data supporting the cardioprotective effect of percutaneous transluminal angioplasty in the perioperative setting are insufficient. beta-blockade has been shown to decrease perioperative mortality and cardiac morbidity in both high-risk (strong evidence) and low-risk (weak evidence) patients.
Conclusions:
coronary revascularization is rarely indicated to simply get the patient through vascular surgery and should be reserved for patients who would need it irrespective of the scheduled vascular procedure. Among all available pharmacological agents, including beta-blockers, alpha-agonists, calcium channel blockers and nitrates, only beta-blockers have been proven to reduce the cardiac risk of vascular surgery.
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