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Antimicrobial and antiproliferative activity of Peucedanum nebrodense (Guss.) Strohl
D Schillaci1, F Venturella, F Venuti
1Dipartimento di Chimica e Tecnologie Farmaceutiche, University of Palermo, Via Archirafi 32, 90123, Palermo, Italy. dschill@unipa.it
Journal of Ethnopharmacology
|June 6, 2003
Abstract:
Acetone extract of Peucedanum nebrodense (Guss.) Strohl., a rare endemic species from the Madonie mountains (Sicily), was tested in vitro for its antimicrobial activity against bacterial reference strains and antiproliferative activity against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and L1210 (murine leukemia) cell lines. The acetone extract showed antiproliferative IC50 values in the range of 14-0.27 microg/ml.