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Substituted hepta-1,6-dien-3-ones with green/fruity odours green/galbanum olfactophore model
Jerzy A Bajgrowicz1, Katja Berg-Schultz, Gerhard Brunner
1Givaudan Schweiz AG, Fragrance Research, Uberlandstrasse 138, CH-8600 Dübendorf, Switzerland. jerzy.bajgrowicz@givaudan.com
Bioorganic & Medicinal Chemistry
|June 6, 2003
Abstract:
Following an analysis of available SAR data on green/galbanum-smelling molecules, a series of new 2-substituted hepta-1,6-dien-3-ones and their analogues were prepared and their olfactory properties evaluated. The study allowed to select efficient new odourants-potential substitutes for natural galbanum oil-and to generate an olfactophore model for the green/galbanum note.