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Kinetic study on the enzymatic resolution of homophenylalanine ester using ionic liquids
Hua Zhao1, Robert G Luo, Sanjay V Malhotra
1Department of Chemistry and Environmental Science, New Jersey Institute of Technology, University Heights, Newark, New Jersey 07102, USA.
Biotechnology Progress
|June 7, 2003
Abstract:
Two ionic liquids (ILs) were investigated as novel media for the enzymatic resolution of amino acid ester to obtain enantiomeric amino acid homophenylalanine. The effects of solvent nature, polarity, and concentration on the kinetic resolution were investigated. With change in solvent concentration, a systematic study shows that an improved enzyme activity can be obtained by adjusting these solvent parameters.