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Related Experiment Videos

Sydenham Chorea in Children.

Lori C. Jordan1, Harvey S. Singer

  • 1Johns Hopkins Hospital, Jefferson Building 1-124, 600 North Wolfe Street, Baltimore, MD 21287, USA. hsinger@jhmi.edu

Current Treatment Options in Neurology
|June 7, 2003
PubMed
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Sydenham chorea, a childhood movement disorder, can cause debilitating symptoms. This review examines potential treatments and dosing for this condition, as robust studies are lacking.

Area of Science:

  • Pediatric Neurology
  • Movement Disorders

Background:

  • Sydenham chorea is a significant cause of acquired chorea in children.
  • Motor symptoms can be debilitating, though often resolve spontaneously.
  • Neuropsychiatric symptoms are common, can precede motor deficits, and cause significant concern.

Purpose of the Study:

  • To review proposed symptomatic treatment options for Sydenham chorea.
  • To discuss dosing strategies for potential therapies.

Main Methods:

  • Review of proposed treatment options.
  • Discussion of dosing strategies.

Main Results:

  • No adequate double-blind, randomized studies currently exist to evaluate symptomatic treatments.

Related Experiment Videos

  • Proposed treatments and dosing strategies are discussed.

    • Conclusions:

    • Further research, including randomized controlled trials, is needed to establish effective symptomatic treatments for Sydenham chorea.
    • Current management relies on reviewing proposed options and strategies due to a lack of definitive evidence.