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Regulation by phosphorylation. Yet another twist in the WASP story
1Centre for Molecular Microbiology and Infection and Department of Biological Sciences, The Flowers Building, Armstrong Road, Imperial College London, SW7 2AZ, London, United Kingdom.
Developmental Cell
|June 7, 2003
Abstract:
Cell migration and other complex cellular processes involve a variety of signaling molecules and require the integration of multiple signals into a coherent cytoskeletal response. Two papers in the May issue of Molecular Cell now demonstrate that phosphorylation plays a critical role in WASP function as a regulator of Arp2/3-mediated actin polymerization.