Related Experiment Video

Updated: Jul 26, 2026

A Model of Chronic Nutrient Infusion in the Rat
08:18

A Model of Chronic Nutrient Infusion in the Rat

Published on: August 14, 2013

Lipogenesis by intact hepatocytes from normal and diabetic rats

E Raghupathy, C Orthlieb, S Abraham

    Lipids
    |November 1, 1975
    PubMed

    Abstract:

    Intact hepatocytes isolated from livers of diabetic rats demonstrate the characteristic decreased lipogenic capacities as compared to normal. Administration of insulin to diabetic rats restores these capacities to near normal levels. The results emphasize the potential that the hepatocyte system has for the study of hormonal regulation of lipogenesis.

    Keywords:
    insulin and lipogenesishepatocyte functiondiabetes and liver metabolismcellular metabolic studies

    More Related Videos

    Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes
    11:03

    Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes

    Published on: September 9, 2021

    Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas
    03:07

    Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas

    Published on: November 11, 2025

    Related Experiment Videos

    Last Updated: Jul 26, 2026

    A Model of Chronic Nutrient Infusion in the Rat
    08:18

    A Model of Chronic Nutrient Infusion in the Rat

    Published on: August 14, 2013

    Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes
    11:03

    Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes

    Published on: September 9, 2021

    Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas
    03:07

    Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas

    Published on: November 11, 2025

    Related Concept Videos

    Type II Diabetes II: Pathophysiology01:24

    Type II Diabetes II: Pathophysiology

    PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.

    Articles linked to this work by shared authors, journal, and citation graph.

    Efficient storage, computation, and exposure of computer-generated holograms by electron-beam lithography.

    Applied optics·2010

    A study of steroid-induced diabetes mellitus in leprosy.

    Indian journal of leprosy·2010

    Genotypic analysis of Mycobacterium leprae strains from different regions of India on the basis of rpoT.

    Indian journal of leprosy·2010

    Contribution of exofacial thiol groups in the reducing activity of Lactococcus lactis.

    The FEBS journal·2010

    Klinefelter's syndrome with renal tubular acidosis: impact on height.

    Singapore medical journal·2010

    Butyrylcholinesterase activity in women with diabetes mellitus in pregnancy: correlation with antioxidant activity.

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2010

    Anticancer Activity of Liposomes Prepared Solely From Cardiolipin.

    Lipids·2026

    RARRES2 Knockdown Attenuates the Partial Macrophage-Like Phenotype and Dysfunction of Vascular Smooth Muscle Cells in an In Vitro Atherosclerosis Model via the NF-κB/NLRP3 Pathway.

    Lipids·2026

    Resolution-Oriented Immunopharmacological Potential of the Lipid Matrix of Rhynchophorus palmarum Larvae in Viral Respiratory Infections: A Perspective Review.

    Lipids·2026

    Circulating Omega-3 Fatty Acids and Cardiometabolic Outcomes: A Systematic Review of Publications From UK Biobank.

    Lipids·2026

    Correlation Between Obesity and Lipid Profile in Patients With Type 2 Diabetes Mellitus and Hypothyroidism.

    Lipids·2026

    A DHA-Deficient Diet Affects the n-3 LC PUFA Molecular Synthesis Pathway and Fatty Acid Composition in European Sardine (Sardina pilchardus).

    Lipids·2026

    Metabolic regulation of stem cell plasticity.

    Current opinion in genetics & development·2026

    Stress-induced remodeling of membrane-bound organelles in budding yeast.

    Current research in microbial sciences·2026

    Nucleotide Metabolism in Health and Disease.

    MedComm·2026

    Glutathione in redox homeostasis: Bridging molecular mechanisms, bioavailability constraints, and translational challenges in systemic therapeutics.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026

    Lactate signaling and lactylation in retina: From physiological Warburg effect to pathological metabolic reprogramming.

    Progress in retinal and eye research·2026

    The quantitative amino acid economy of yeast reveals public versus private goods and guides syntrophic community design.

    mSystems·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us