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Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
Published on: May 2, 2018
Health effects of indoor fungal bioaerosol exposure
Frederick Fung1, William G Hughson
1Department of Occupational Medicine, Sharp Rees-Stealy Medical Group, San Diego, California, USA.
Abstract:
Occupational and environmental health professionals are confronted with issues concerning the health effects of indoor fungal bioaerosol exposure. This article reviews current data on the health effects of indoor mold exposure and provides practical suggestions for occupational and environmental health practitioners regarding how best to manage these exposures based on published human studies. We conducted MEDLINE searches and reviewed all English language studies on indoor mold exposure (visible survey or objective sampling) and human health effects published from 1966 to November 2002. The main findings of the studies are analyzed in conjunction with plausible association of health effects and fungal exposure. Five case control studies, 17 cross-sectional surveys, and 7 case reports met the selection criteria. Current evidence suggests that excessive moisture promotes mold growth and is associated with an increased prevalence of symptoms due to irritation, allergy, and infection. However, specific human toxicity due to inhaled fungal toxins has not been scientifically established. Methods for measuring indoor bioaerosol exposure and health assessment are not well standardized, making interpretation of existing data difficult. Additional studies are needed to document human exposure-disease and dose-response relationships.
Insights
Indoor mold exposure, often caused by excessive moisture, is linked to irritation, allergy, and infection symptoms. However, scientific proof of fungal toxin toxicity in humans remains elusive.
Area of Science:
- Environmental Health
- Occupational Health
- Mycology
Background:
- Occupational and environmental health professionals face challenges in assessing indoor fungal bioaerosol exposure.
- Current data on health effects of indoor mold exposure requires synthesis for practical management strategies.
Observation:
- A comprehensive review of human studies from 1966 to 2002 was conducted using MEDLINE searches.
- Studies included visible surveys, objective sampling, case control studies, cross-sectional surveys, and case reports.
Findings:
- Excessive moisture promotes mold growth, correlating with increased prevalence of irritation, allergy, and infection symptoms.
- Scientific evidence establishing specific human toxicity from inhaled fungal toxins is currently lacking.
- Standardization of indoor bioaerosol exposure measurement and health assessment methods is poor, complicating data interpretation.
Implications:
- Further research is crucial to establish definitive human exposure-disease and dose-response relationships.
- Improved standardization in exposure assessment and health evaluation is needed for better management of indoor mold-related health issues.
- Occupational and environmental health practitioners require evidence-based guidance for managing indoor fungal exposures.
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