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Updated: Sep 25, 2026

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Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Comparison of microscan broth microdilution, synergy quad plate agar dilution, and disk diffusion screening methods
David R Murdoch1, Stanley Mirrett, Lizzie J Harrell
1Clinical Microbiology Laboratory, Duke University Medical Center, Durham, North Carolina 27710, USA. david.murdoch@cdhb.govt.nz
Journal of Clinical Microbiology
|June 7, 2003
Abstract:
We compared the dried MicroScan microdilution panel, Synergy Quad plate agar dilution, and high-potency disk diffusion screening methods for the detection of high-level aminoglycoside resistance in 815 enterococcal bloodstream isolates. Agreement between the three methods was 99% when testing for high-level gentamicin resistance and 96% when testing for high-level streptomycin resistance.
