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Updated: Aug 27, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Predictive factors of complications after coronary stent implantation
Alexandre Schaan de Quadros1, Carlos A M Gottschall, Rogério Sarmento-Leite
1Instituto de Cardiologia do Rio Grande do Sul, Fundação Universitária de Cardiologia. pesquisa@cardnet.tche.br
Insights
Predictive factors for complications after coronary stent implantation include stent design, lesion complexity, and thrombus presence. Angiographic variables and techniques significantly influence procedural outcomes and patient safety.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Device Technology
Background:
- Coronary stent implantation is a common procedure for treating coronary artery disease.
- Understanding factors predicting complications is crucial for improving patient outcomes.
- Previous studies have identified various risk factors, but the influence of stent design requires further investigation.
Purpose of the Study:
- To identify independent predictive factors for major cardiovascular complications following coronary stent implantation.
- To analyze the impact of clinical and angiographic characteristics on in-hospital complications.
- To assess the role of stent design in procedural success and complication rates.
Main Methods:
- A consecutive cohort study involving 1018 patients undergoing 1070 stent implantations.
- Analysis of clinical and angiographic data, including lesion complexity and thrombus presence.
- Statistical analysis using a stepwise backwards multiple logistic regression model to determine independent predictors of complications.
Main Results:
- The overall incidence of major cardiovascular complications was 7.9%.
- Independent predictors of complications included rescue stent use (OR=5.1), filamentary stent design (OR=4.5), first-generation tubular stent (OR=2.4), multiple stents (OR=3), lesion complexity (OR=2.4), and thrombus (OR=2).
- High rates of angiographic (96.8%) and clinical (91%) success were achieved.
Conclusions:
- Angiographic variables and procedural techniques are critical determinants of complication risk.
- Stent design, including type and number, significantly influences the outcome of coronary stent implantation.
- These findings underscore the importance of careful patient selection and procedural planning to minimize complications.
Objective:
To analyze the predictive factors of complications after implantation of coronary stents in a consecutive cohort study.
Methods:
Clinical and angiographic characteristics related to the procedure were analyzed, and the incidence of major cardiovascular complications (myocardial infarction, urgent surgery, new angioplasty, death) in the in-hospital phase were recorded. Data were stored in an Access database and analyzed by using the SPSS 6.0 statistical program and a stepwise backwards multiple logistic regression model.
Results:
One thousand eighteen (mean age of 61 +/-11 years, 29% females) patients underwent 1070 stent implantations. The rate of angiographic success was 96.8%, the rate of clinical success was 91%, and the incidence of major cardiovascular complications was 7.9%. The variables independently associated with major cardiovascular complications, with their respective odds ratio (OR) were: rescue stent, OR = 5.1 (2.7-9.6); filamentary stent, OR = 4.5 (2.2-9.1); first-generation tubular stent, OR = 2.4 (1.2-4.6); multiple stents, OR = 3 (1.6-5.6); complexity of the lesion, OR = 2.4 (1.1-5.1); thrombus, OR = 2 (1.1-3.5).
Conclusion:
The results stress the importance of angiographic variables and techniques in the risk of complications and draw attention to the influence of the stent's design on the result of the procedure.
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