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Osteonecrosis in patients with SLE.
Mahmoud Abu-Shakra1, Dan Buskila, Yehuda Shoenfeld
1Autoimmune Rheumatic Diseases Unit and Departments of Medicine B & D, Soroka Medical Center, Beer-Sheva, Israel.
Clinical Reviews in Allergy & Immunology
|June 10, 2003
Summary
Osteonecrosis, bone death due to disrupted blood supply, is linked to systemic lupus erythematosus (SLE). This review covers causes, diagnosis, and treatment for osteonecrosis in SLE patients.
Area of Science:
- Rheumatology
- Orthopedics
- Pathology
Background:
- Osteonecrosis, also known as avascular necrosis, involves bone death from interrupted blood supply.
- It presents as post-traumatic or nontraumatic, with the latter linked to systemic conditions.
- Systemic lupus erythematosus (SLE) shows a strong association with osteonecrosis.
Purpose of the Study:
- To review the causes, clinical and epidemiological features, diagnosis, and treatment of osteonecrosis in patients with SLE.
Main Methods:
- Literature review of osteonecrosis in SLE patients.
Main Results:
- Osteonecrosis is a known complication in SLE.
- Various systemic diseases and conditions are associated with nontraumatic osteonecrosis.
- This review synthesizes current knowledge on osteonecrosis in SLE.
Conclusions:
- Osteonecrosis is a significant concern in SLE management.
- Understanding its various facets is crucial for timely diagnosis and effective treatment.
- Further research may elucidate specific treatment strategies for osteonecrosis in SLE.