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Related Experiment Videos

Juvenile osteoporosis: recognizing the risk.

L Lyndon Key1, William Ries, Prema Madyastha

  • 1Medical University of South Carolina, Department of Pediatrics, Charleston, SC 29425, USA. keyl@musc.edu

Journal of Pediatric Endocrinology & Metabolism : JPEM
|June 11, 2003
PubMed
Summary

Children with multiple fractures often have undiagnosed osteoporosis. Bone mineral density (BMD) screening is crucial for pediatric patients experiencing recurrent fractures, revealing significant bone density deficits.

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Area of Science:

  • Pediatric Endocrinology
  • Pediatric Orthopedics
  • Bone Metabolism

Background:

  • Osteoporosis in children is frequently undiagnosed, with diagnosis often delayed until fractures occur.
  • Radiographs may show hypodense bones, but the link between bone mineral density (BMD) and fracture risk in pediatric populations remains debated.

Purpose of the Study:

  • To investigate the prevalence of osteoporosis in pediatric patients presenting with multiple fractures.
  • To assess the utility of bone mineral density (BMD) measurements in identifying osteoporosis in this cohort.

Main Methods:

  • Retrospective review of 16 pediatric patients (ages 5-15) with at least two fractures from minimal trauma.
  • Dual-energy X-ray absorptiometry (DEXA) scans were utilized to measure bone mineral density (BMD) at the hip and spine.

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Main Results:

  • The mean Z-scores for hip and spine BMD were -2.78 and -3.08, respectively.
  • Fifteen out of 16 patients exhibited osteopenia or osteoporosis in either the hip or spine.
  • Twelve patients were diagnosed with osteoporosis in both hip and spine, with one diagnosed in the spine only.

Conclusions:

  • Pediatric patients with recurrent fractures and minimal trauma show a high prevalence of osteoporosis.
  • Screening for osteoporosis using bone mineral density (BMD) assessment is strongly recommended for children with multiple fractures.