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Malnutrition at age 3 years and lower cognitive ability at age 11 years: independence from psychosocial adversity
Jianghong Liu1, Adrian Raine, Peter H Venables
1School of Nursing, University of California, Los Angeles.
Insights
Early childhood malnutrition is linked to long-term cognitive deficits, persisting into age 11 years. Nutritional interventions in early life may improve cognitive development and academic outcomes.
Area of Science:
- Developmental Psychology
- Nutritional Science
- Public Health
Background:
- Early malnutrition is a known risk factor for impaired cognitive development.
- Long-term cognitive sequelae of early malnutrition require further investigation.
- Controlling for psychosocial factors is crucial in assessing malnutrition's independent effects on cognition.
Purpose of the Study:
- To investigate the association between malnutrition at age 3 years and cognitive ability at age 11 years.
- To determine if this association persists independently of psychosocial confounds.
- To examine the long-term impact of early nutritional status on cognitive function.
Main Methods:
- Prospective longitudinal study of a birth cohort (n=1559).
- Assessment of malnutrition indicators (hemoglobin, angular stomatitis, kwashiorkor, hair quality) at age 3 years.
- Cognitive abilities (verbal, spatial, reading, scholastic, neuropsychological) measured at ages 3 and 11 years.
Main Results:
- Malnourished children exhibited poorer cognitive performance at both ages 3 and 11 years.
- Cognitive deficits remained stable over time and were consistent across sex and ethnic groups.
- Children with three malnutrition indicators showed a 15.3-point deficit in IQ at age 11, independent of psychosocial adversity.
Conclusions:
- Early malnutrition at age 3 years is significantly associated with poorer cognitive ability at age 11 years.
- This association is independent of psychosocial adversity, highlighting nutrition's critical role.
- Improving early childhood nutrition is recommended to enhance long-term cognitive development and school performance.
Background:
Early malnutrition is linked to poor cognition, but long-term effects have not been extensively examined and psychosocial confounds have not always been controlled.
Objective:
To test the hypothesis that malnutrition at age 3 years will be associated with poorer cognitive ability at age 11 years independent of psychosocial confounds.
Design:
A prospective, longitudinal study of a birth cohort of 1559 children originally assessed at age 3 years for malnutrition (low hemoglobin level, angular stomatitis, kwashiorkor, and sparse, thin hair) and followed up to age 11 years.
Setting And Participants:
A community sample of 1559 children (51.4% boys and 48.6% girls) born between September 1, 1969, and August 31, 1970, in 2 towns in the island of Mauritius, with 68.7% Indians and 25.7% Creoles (African origin).
Main Outcome Measures:
Verbal and spatial ability measured at ages 3 and 11 years and reading, scholastic ability, and neuropsychologic performance measured at age 11 years.
Results:
Malnourished children had poorer cognition at both ages. Deficits were stable across time, applied to all sex and ethnic groups, and remained after controlling for multiple measures of psychosocial adversity. Children with 3 indicators of malnutrition had a 15.3-point deficit in IQ at age 11 years.
Conclusions:
Malnutrition at age 3 years is associated with poor cognition at age 11 years independent of psychosocial adversity. Promoting early childhood nutrition could enhance long-term cognitive development and school performance, especially in children with multiple nutritional deficits.
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