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Axial length-disc area ratio in esotropic amblyopia
1College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA. EYECHARTPLUS@AOL.COM
Archives of Ophthalmology (Chicago, Ill. : 1960)
|June 11, 2003
Summary
Hyperopic strabismus and amblyopia are linked to significantly smaller optic disc areas (DAs). This study found reduced optic disc size in eyes with hyperopic strabismus and amblyopia compared to those without these conditions.
Area of Science:
- Ophthalmology
- Optometry
- Pediatric eye care
Background:
- Hyperopia is a known risk factor for developing esotropia and amblyopia.
- Previous research suggests reduced disc areas (DAs) in individuals with amblyopia.
Purpose of the Study:
- To investigate differences in relative optic disc size between hyperopic eyes without strabismus or amblyopia and those with esotropia and amblyopia.
- To evaluate the relationship between axial length (AXL) and DA in subjects with hyperopia.
Main Methods:
- Analysis of 850 patient records, identifying 122 subjects with bilateral refractive errors exceeding +2.00 diopters.
- Objective measurement of disc areas (DAs) and axial lengths (AXLs) via ultrasonographic biometry.
- Calculation of the AXL/DA ratio for comparative analysis.
Main Results:
- The mean AXL/DA ratio was significantly higher in the hyperopic strabismus group (12.30 mm) compared to the hyperopia-only group (9.48 mm) (P =.01).
- Amblyopic eyes exhibited a higher mean AXL/DA ratio (15.24 mm) than their nonamblyopic fellow eyes (13.61 mm) (P =.02).
Conclusions:
- Eyes with hyperopic strabismus, with or without amblyopia, demonstrate disproportionately reduced optic disc areas.
- These findings suggest a potential link between optic disc size and the development of strabismus and amblyopia in hyperopic individuals.
