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[Multiple intracranial and spinal meningiomas]
1Neurochirurgische Klinik Kantonspital, St. Gallen.
Abstract:
Meningeomas are regarded as benign tumors that as a rule can be totally removed. The great prevalence of the benign types of meningeomas does not exclude their recurrence. In some cases (6-8% in the recent literature) a solitary globular tumor represents only the most visible actual growth in context of a systemic tumoral disease spreading over a wide area of arachnoid with simultaneous or delayed growth. In a series of 188 patients operated in St. Gall because of meningeomas, 13 (8%) have multiple simultaneous or delayed tumors, in one case in the spine, without neurofibromatosis. Several operations had to be performed on each patient. The prognosis quoad valetudinem is eventually worse than a solitary tumor. We present a detailed description of our cases and a résume of the literature.
Insights
Meningiomas, often benign, can recur and spread systemically. This study highlights that 8% of patients experienced multiple tumors, impacting prognosis.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Meningiomas are typically considered benign and fully removable.
- However, recurrence and systemic spread can occur even with benign types.
Observation:
- A series of 188 patients with meningiomas were reviewed.
- 13 patients (8%) presented with multiple simultaneous or delayed tumors, including one spinal case without neurofibromatosis.
Findings:
- A significant minority of meningioma cases (8%) exhibit multifocal disease.
- These multifocal meningiomas require multiple surgical interventions.
- The presence of multiple tumors negatively impacts patient prognosis.
Implications:
- Highlights the importance of considering systemic disease in meningioma diagnosis.
- Suggests a need for vigilant long-term surveillance for recurrence and new tumor development.
- Emphasizes the complex management and poorer prognosis associated with multifocal meningiomas.