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Updated: Sep 25, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
Published on: September 30, 2021
Successful treatment with recombinant factor VIIa for intractable bleeding at pelvic surgery
Jarosław Daniloś1, Andrzej Goral, Piotr Paluszkiewicz
1First Department of Gynecology, Medical University, Lublin, Poland. obgyn@panaceum.am.lublin.pl
Background:
Postoperative bleeding may be complicated by failure to identify the site of bleeding, multiple bleeding points, and persistent hemorrhage despite surgical intervention.
Case:
Activated recombinant factor VII was used successfully in a patient with life-threatening postsurgical bleeding after resection of two large extraperitoneal pelvic sarcomas.
Conclusion:
In severe hemorrhage, hemostasis can be achieved with activated recombinant factor VII.
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