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Updated: Sep 25, 2026

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
Published on: March 14, 2011
[Allogeneic adoptive immunotherapy]
P Tiberghien1, E Robinet, C Ferrand
1Inserm EPI 0119/Upres EA 2284, Etablissement français du Sang Bourgogne-Franche-Comté, université de Franche-Comté, 1, boulevard Alexandre-Fleming, BP 1937, 25020 cedex, Besançon, France. pierre.tiberghien@efs.sante.fr <pierre.tiberghien@efs.sante.fr>
Recognition of the importance of immune cells present in a hematopoietic graft has resulted in a significant change in the perception of allogeneic hematopoietic transplantation. Such a transplant modality is now perceived has a very efficient form of adoptive allogeneic immunotherapy unfortunately associated with significant toxicity.
Recognition of the importance of immune cells present in a hematopoietic graft has resulted in a significant change in the perception of allogeneic hematopoietic transplantation. Such a transplant modality is now perceived has a very efficient form of adoptive allogeneic immunotherapy unfortunately associated with significant toxicity.
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