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Evaluation of anti-hsp70 antibody screening in sudden deafness
Anna-Karin Samuelsson1, Dag Hydén, Magnus Roberg
1Division of Rheumatology, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linköping University Hospital, Linköping, Sweden.
Ear and Hearing
|June 12, 2003
Abstract
Objective:
To assess the diagnostic utility of anti-hsp70 antibody screening in sudden deafness.
Designs:
era from 27 patients with sudden deafness and 100 healthy blood donors were analyzed by Western blotting (WB) for the presence of antibodies against 68 kD heat shock protein (anti-hsp70).
Results:
19% of the patient sera and 14% of the control sera turned out positive, which was not significantly different.
Conclusions:
The anti-hsp70 WB test lacks clinical utility for diagnostic screening in patients with sudden deafness.