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Updated: Sep 25, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
A holistic programmatic approach to natural hormone replacement
Paula J Watt1, Robbie B Hughes, Linda B Rettew
1The Joseph F. Sullivan Center, Charleston, SC, USA.
Abstract:
With an unprecedented number of women reaching midlife, the impact of menopause has become a significant public health issue. Recent findings have left women and practitioners questioning traditional hormone replacement therapy (HRT) and searching for reasonable alternatives. Growing numbers of women in this country are choosing to use natural progesterone and estrogen to treat symptoms of menopause. This article describes a program that focuses on education, client participation, and alternative methodology to support individualized HRT therapy using natural compounded bio-identical hormones.
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