Development and validation of a web-based screening tool for monitoring cognitive status

We acquired normative data for an Internet neurocognitive screening tool, the Cognitive Stability Index (CSI), and investigated its validity both for initial assessment and for detecting significant change.

Normative data on a nationally representative sample of 284 individuals aged 18 to 89. Validity data was obtained for outpatient groups of mild-to-moderate TBI, attention deficit/hyperactivity disorder (AD/HD), and Alzheimer's disease.

The CSI subtests resolve to four factors: attention, processing speed, motor speed, and memory with acceptable psychometric properties. Patterns of scores obtained by three groups of patient-participants provided reasonable evidence of clinical validity for screening and monitoring change.

An Internet-based system holds promise for applying complex statistical models for routine monitoring of cognitive function.