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[Laryngeal sarcoidosis: a case report].
P Ezcurra Hernández1, A Albertí i Casas, E Figuerola Massana
1Servicio de Otorrinolaringología, Hospital Universitari Joan XXIII, Tarragona.
Acta Otorrinolaringologica Espanola
|June 14, 2003
Summary
Sarcoidosis, a rare granulomatous disease, can affect the larynx, causing symptoms like voice changes and sleep apnea. This case highlights the importance of considering sarcoidosis in young adults with these respiratory complaints.
Area of Science:
- Pulmonology
- Otolaryngology
- Pathology
Background:
- Sarcoidosis is a chronic, multisystemic granulomatous disease of unknown cause, primarily affecting young adults.
- Commonly presents with bilateral hilar adenopathies, interstitial lung infiltrates, and skin/ocular lesions.
- Laryngeal involvement is infrequent but can significantly impact quality of life.
Observation:
- A 26-year-old male presented with a three-month history of globus sensation, hoarseness, loud snoring, and obstructive sleep apnea.
- Clinical presentation suggested laryngeal pathology.
- Diagnostic workup included history, radiology, and pathological examination.
Findings:
- Pathological examination confirmed laryngeal noncaseating granulomatous infiltration.
- Diagnosis of laryngeal sarcoidosis was established.
- The condition demonstrated a tendency towards spontaneous regression.
Implications:
- Laryngeal sarcoidosis requires a high index of suspicion, especially in young adults with unexplained upper airway symptoms.
- Treatment is primarily symptomatic, often involving corticosteroids (systemic or aerosolized).
- Micro-surgical excision or tracheotomy may be considered for refractory cases or airway compromise.