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Published on: August 24, 2019
[Pyogenic liver abscess--an unusual presentation of colonic villous adenoma]
Adi Leiba1, Sara Apter, Irit Avni
1Department of Medicine D, Sheba Medical Center, Tel Hashomer, Israel.
Abstract:
A pyogenic liver abscess is a final common pathway of many pathologic processes, mainly suppurative cholangitis or suppurative pyephlebitis, arising from abdominal or pelvic infection. There are many other etiologies, and some abscesses are idiopathic-namely, cryptogenic abscess. We present a case of a man with a pyogenic liver abscess. This was the clue for the diagnosis of a large but clinically silent villous adenoma of the colon. Colonic tumors, manifested clinically as an hepatic abscess, in the absence of liver metastases, are very uncommon. This is the first description of a villous adenomatous tumor with such a presentation.
Insights
A pyogenic liver abscess can indicate underlying colon cancer. This case highlights a rare instance where a liver abscess led to the diagnosis of a silent villous adenoma, a colonic tumor.
Area of Science:
- Gastroenterology
- Hepatology
- Oncology
Background:
- Pyogenic liver abscesses result from various infections, often originating in the abdomen or pelvis.
- While common causes include cholangitis and pyephlebitis, some liver abscesses are cryptogenic (idiopathic).
- Colonic tumors rarely present as hepatic abscesses without liver metastases.
Observation:
- A case study involving a male patient presenting with a pyogenic liver abscess.
- The liver abscess served as the initial diagnostic clue.
- Further investigation revealed a large, clinically silent villous adenoma of the colon.
Findings:
- The patient's pyogenic liver abscess was found to be caused by an underlying villous adenoma of the colon.
- This presentation is highly unusual, as colonic tumors typically do not manifest as hepatic abscesses without liver metastases.
- This case represents the first documented instance of a villous adenoma presenting in this manner.
Implications:
- Highlights the importance of considering colorectal malignancy in the differential diagnosis of pyogenic liver abscesses, even without typical metastatic signs.
- Suggests that occult gastrointestinal pathology should be investigated in patients with unexplained liver abscesses.
- Underscores the diagnostic challenge posed by rare presentations of common diseases.
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