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Abscess within a glioblastoma multiforme--case report

M Ichikawa1, Y Shimizu, M Sato

  • 1Department of Neurosurgery, Shimizu Hospital, Kyoto.

Neurologia Medico-Chirurgica
|October 1, 1992
PubMed

Insights

A rare brain abscess within a glioblastoma presented unusually with stroke-like symptoms. Surgical removal and histology confirmed glioblastoma, highlighting diagnostic challenges.

Area of Science:

  • Neuro-oncology
  • Neuropathology
  • Neuroradiology

Background:

  • Glioblastoma is an aggressive primary brain tumor.
  • Intracranial abscesses can mimic other neurological conditions.
  • Distinguishing between tumor and abscess is critical for effective treatment.

Purpose of the Study:

  • To report a rare case of abscess within a glioblastoma.
  • To describe the unusual clinical and imaging presentation.
  • To emphasize diagnostic considerations in complex brain lesions.

Main Methods:

  • Case presentation of a 46-year-old female with hemiparesis and seizure.
  • Diagnostic imaging including computed tomography (CT) and magnetic resonance imaging (MRI).
  • Image-guided aspiration and subsequent surgical resection with histological examination.

Main Results:

  • Imaging revealed hemorrhage mimicking infarction, later showing ring enhancement.
  • Aspiration confirmed an abscess, which recurred after initial drainage.
  • Histological analysis of the resected mass revealed glioblastoma.

Conclusions:

  • Abscess formation within a glioblastoma is rare and presents diagnostic challenges.
  • Ring-enhancing lesions require thorough investigation to differentiate between tumor and infection.
  • This case underscores the importance of integrating clinical, imaging, and pathological findings.

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