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Updated: Sep 25, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
Published on: October 8, 2017
Locally-adaptive and memetic evolutionary pattern search algorithms
1Sandia National Laboratories, P.O. Box 5800, MS 1110, Albuquerque, NM 87185-1110, USA. wehart@sandia.gov
Abstract:
Recent convergence analyses of evolutionary pattern search algorithms (EPSAs) have shown that these methods have a weak stationary point convergence theory for a broad class of unconstrained and linearly constrained problems. This paper describes how the convergence theory for EPSAs can be adapted to allow each individual in a population to have its own mutation step length (similar to the design of evolutionary programing and evolution strategies algorithms). These are called locally-adaptive EPSAs (LA-EPSAs) since each individual's mutation step length is independently adapted in different local neighborhoods. The paper also describes a variety of standard formulations of evolutionary algorithms that can be used for LA-EPSAs. Further, it is shown how this convergence theory can be applied to memetic EPSAs, which use local search to refine points within each iteration.
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