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Interventions for treating trichomoniasis in women
1Department of Gynecology and Obstetrics, Emory University School of Medicine, 69 Butler Street, S.E., Atlanta, Georgia 30303, USA. fatuforna@hotmail.com
The Cochrane Database of Systematic Reviews
|June 14, 2003
Summary
Single-dose nitroimidazole drugs effectively treat trichomoniasis in women. Partner treatment is crucial for preventing reinfections and reducing the overall prevalence of this common sexually transmitted infection.
Area of Science:
- Infectious Diseases
- Women's Health
- Public Health
Background:
- Trichomoniasis, caused by Trichomonas vaginalis, affects approximately 120 million women globally each year.
- This sexually transmitted infection is a significant public health concern, potentially increasing HIV transmission rates.
Purpose of the Study:
- To evaluate the efficacy of diverse treatment strategies for managing trichomoniasis in women.
- To synthesize evidence from randomized controlled trials on various anti-trichomonal treatments.
Main Methods:
- A comprehensive literature search was conducted across major databases (Cochrane, MEDLINE, EMBASE) up to November 2002.
- Included were randomized or quasi-randomized trials comparing different anti-trichomonal drugs, doses, or placebo/no treatment.
- Trial quality assessment and data extraction were performed independently by two reviewers.
Main Results:
- Fifty-four trials were analyzed, indicating that nitroimidazole drugs are effective for short-term parasitological cure.
- Treatment of sexual partners was found to be effective in reducing long-term reinfection rates.
Conclusions:
- A single oral dose of nitroimidazole can achieve parasitological cure for trichomoniasis.
- Future research should prioritize developing effective partner treatment strategies to curb reinfections and lower disease prevalence.