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Fragrance material review on linalyl hexanoate
C S Letizia1, J Cocchiara, J Lalko
1Research Institute for Fragrance Materials, Inc. 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. letizia@rifm.org
Summary
This review examines the toxicologic and dermatologic safety of linalyl hexanoate, a common fragrance ingredient. Findings support its safe use in cosmetic products based on current data.
Area of Science:
- Toxicology
- Dermatology
- Cosmetic Science
Background:
- Linalyl hexanoate is widely utilized as a fragrance ingredient in various consumer products.
- Understanding its toxicologic and dermatologic profile is crucial for consumer safety.
Purpose of the Study:
- To conduct a comprehensive toxicologic and dermatologic review of linalyl hexanoate.
- To assess the safety of linalyl hexanoate for use as a fragrance ingredient.
Main Methods:
- Literature review of existing toxicologic and dermatologic studies.
- Analysis of data pertaining to skin irritation, sensitization, and systemic toxicity.
Main Results:
- Available data suggest a low potential for skin irritation and sensitization.
- No significant systemic toxicity concerns were identified at typical exposure levels.
Conclusions:
- Linalyl hexanoate is considered safe for use as a fragrance ingredient based on current toxicologic and dermatologic assessments.
- Further research may be warranted to address specific data gaps, if any.