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Related Concept Videos

Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
Synteny and Evolution02:31

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...

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Related Experiment Video

Updated: Jul 12, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Phylogenomics: intersection of evolution and genomics.

Jonathan A Eisen1, Claire M Fraser

  • 1Institute for Genomic Research, Rockville, MD 20850, USA. jeisen@tigr.org

Science (New York, N.Y.)
|June 14, 2003
PubMed
Summary
This summary is machine-generated.

Genomic and evolutionary studies offer valuable insights into species. Integrating these perspectives through phylogenomics promises significant advancements in biological research.

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Last Updated: Jul 12, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
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Published on: August 14, 2018

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Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
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Area of Science:

  • Genomics
  • Evolutionary Biology
  • Phylogenetics

Background:

  • Genomic studies have significantly advanced our understanding of species.
  • Evolutionary studies provide crucial context for biological diversity.

Purpose of the Study:

  • To highlight the benefits of integrating genomic and evolutionary perspectives.
  • To propose an integrated phylogenomic approach for enhanced biological insights.

Main Methods:

  • Review of existing genomic and evolutionary research.
  • Conceptual framework for integrating diverse biological data.

Main Results:

  • Genomic and evolutionary studies yield substantial knowledge.
  • Integration of these fields offers synergistic advantages.

Conclusions:

  • An integrated phylogenomic approach is highly beneficial.
  • Combining genomic and evolutionary data enhances species research.