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Release from transdermal delivery systems. Application of a new non isothermic method to Trans-Ver-Sal patches
G Alibrandi1, S Coppolino, N Micali
1Dipartimento di Chimica Inorganica, Chimica Analitica e Chimica Fisica, Università di Messina, Messina, Italia.
Bollettino Chimico Farmaceutico
|June 17, 2003
Abstract:
In this paper a new non isothermic method for the determination of the release drug rate constant (k) from a transdermal delivery system is proposed. The new method was applied to transdermal patches Trans-Ver-Sal. The results obtained prove to be able to release salicylic acid of transdermal system and the effectiveness of the new method propose.