[The onset of adverse events induced by chemotherapy for patients with malignancy]

Chemotherapy is frequently adopted for patients with malignancy, as one of type of multidisciplinary treatment. Each chemotherapeutic drug has the potential to induce various adverse events in the patients receiving chemotherapy. Before the application of chemotherapy, sufficient knowledge for chemotherapeutic drugs and careful evaluation for patients are indispensable to avoid severe adverse events, since uncontrolled adverse events cause a markedly lower quality of life, incompletion of the treatment modality and life-threatening of patients. The onset of each adverse event is influenced by the host condition, e.g., sex, age, allergic status, complication, nutritional condition, the administration method, e.g., dose, route, course, combined agents, and combined therapy, e.g., radiotherapy. Frequent adverse events are discussed in terms of the onset.