Related Experiment Video
Updated: Sep 25, 2026

Mouse Model of Pressure Ulcers After Spinal Cord Injury
Published on: March 9, 2019
Use of behavioral contingencies to promote prevention of recurrent pressure ulcers
Michael L Jones1, Cynthia S Mathewson, Vincent K Adkins
1Crawford Research Institute, Shepherd Center, Atlanta, GA 30309, USA. mike_jones@shepherd.org
Objective:
To determine effectiveness of an intervention using monetary rewards as a consequence for preventing or reducing severity of pressure ulcers in spinal cord injury (SCI) patients with a history of chronic, recurrent ulcers.
Design:
Multiple baseline analysis across subjects (time-lagged control), comparing severity of pressure ulcers and treatment costs during baseline and intervention.
Setting:
Outpatient wound-care clinic of private, nonprofit specialty hospital.
Participants:
Nine adults (all with paraplegia) with a history of hospitalizations for treatment of pressure ulcers.
Interventions:
In study 1, participants (n=6) undertook (1) a comprehensive self-care plan, (2) had a graduated schedule of visits with an advanced practice nurse, and (3) received monetary rewards for successfully preventing serious ulcers. In study 2, participants (n=3) undertook interventions 1 and 2, but monetary rewards were in staged phases so a component analysis could compare the effectiveness of visits alone to visits plus monetary rewards.
Main Outcome Measures:
Severity of pressure ulcers measured with the Pressure Ulcer Scale for Healing (PUSH Tool 3.0); and direct costs of treatment and preventive care for pressure ulcers.
Results:
In study 1, severity of pressure ulcers-and their related treatment costs-decreased for the 6 participants. Maintenance of effects postintervention was highly variable, with only 3 participants showing long-term improvements. In study 2, for 2 participants, visits alone did not reduce pressure ulcer severity, but visits plus payments did effectively reduce ulcer severity, indicating improved prevention behaviors.
Conclusions:
Findings support the assumption that pressure ulcers may recur among some individuals because there are insufficient positive consequences for effective prevention.
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