Brain repair by cell replacement and regeneration

STEM-PD trial protocol: a multi-centre, single-arm, first-in-human, dose-escalation trial, investigating the safety and tolerability of intraputamenal transplantation of human embryonic stem cell-derived dopaminergic cells for Parkinson's disease.

BMJ open·2025

Human cortical neurons rapidly generated by embryonic stem cell programming integrate into the stroke-injured rat cortex.

Stem cells (Dayton, Ohio)·2025

The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease.

Nature biotechnology·2025

History of cellular grafting for central nervous system repair-A clinical perspective.

Handbook of clinical neurology·2024

Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD.

Cell stem cell·2023

Oligodendrocytes in human induced pluripotent stem cell-derived cortical grafts remyelinate adult rat and human cortical neurons.

Stem cell reports·2023

Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases.

Proceedings of the National Academy of Sciences of the United States of America·2026

Alpha rhythms in the left auditory cortex set the speed limit for speech comprehension.

Proceedings of the National Academy of Sciences of the United States of America·2026

A population of primary afferent sensory neurons mediates pain relief through nocifensive coping behavior in mice.

Proceedings of the National Academy of Sciences of the United States of America·2026

Evidence of intertwined pair density and charge density wave orders in UTe<sub>2</sub>.

Proceedings of the National Academy of Sciences of the United States of America·2026

Mitofusin-2 in ventral striatal D1 neurons regulates effort-based motivation through sex-specific mitochondrial-synaptic reprogramming.

Proceedings of the National Academy of Sciences of the United States of America·2026

Plants are a powerful proxy for global tidal marsh methane fluxes.

Proceedings of the National Academy of Sciences of the United States of America·2026

Microbiota-gut-brain axis imbalance: a promising therapeutic target for preserving brain health in high-altitude environment.

Frontiers in neuroscience·2026

A dual-prototype morphological topology evolution network for clinically oriented brain tumor MRI segmentation.

Frontiers in oncology·2026

Nose-to-brain delivery of candesartan-loaded nanoemulsion: brain biodistribution and neurobehavioral outcomes in controlled cortical impact-induced traumatic brain injury.

Inflammopharmacology·2026

Enhancing brain delivery of tegaserod for Alzheimer's disease: a pharmaceutical comparison of two nanocarrier-based strategies.

International journal of pharmaceutics·2026

Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita.

PloS one·2026

Prediction of migraine treatment response with clinical and genetic data: A machine learning analysis of the HUNT study.

Cephalalgia : an international journal of headache·2026

Related Experiment Videos

Brain repair by cell replacement and regeneration

Related Concept Videos

STEM-PD trial protocol: a multi-centre, single-arm, first-in-human, dose-escalation trial, investigating the safety and tolerability of intraputamenal transplantation of human embryonic stem cell-derived dopaminergic cells for Parkinson's disease.

Human cortical neurons rapidly generated by embryonic stem cell programming integrate into the stroke-injured rat cortex.

The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease.

History of cellular grafting for central nervous system repair-A clinical perspective.

Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD.

Oligodendrocytes in human induced pluripotent stem cell-derived cortical grafts remyelinate adult rat and human cortical neurons.

Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases.

Alpha rhythms in the left auditory cortex set the speed limit for speech comprehension.

A population of primary afferent sensory neurons mediates pain relief through nocifensive coping behavior in mice.

Evidence of intertwined pair density and charge density wave orders in UTe<sub>2</sub>.

Mitofusin-2 in ventral striatal D1 neurons regulates effort-based motivation through sex-specific mitochondrial-synaptic reprogramming.

Plants are a powerful proxy for global tidal marsh methane fluxes.

Microbiota-gut-brain axis imbalance: a promising therapeutic target for preserving brain health in high-altitude environment.

A dual-prototype morphological topology evolution network for clinically oriented brain tumor MRI segmentation.

Nose-to-brain delivery of candesartan-loaded nanoemulsion: brain biodistribution and neurobehavioral outcomes in controlled cortical impact-induced traumatic brain injury.

Enhancing brain delivery of tegaserod for Alzheimer's disease: a pharmaceutical comparison of two nanocarrier-based strategies.

Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita.

Prediction of migraine treatment response with clinical and genetic data: A machine learning analysis of the HUNT study.

Related Experiment Videos

Brain repair by cell replacement and regeneration

Related Concept Videos

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