Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Screening for infectious diseases.

Stefan Gerber1, Patrick Hohlfeld

  • 1Department Gynecology and Obstetrics, CHUV, 1011 Lausanne, Switzerland. Stefan.Gerber@chuv.hospvd.ch

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|June 18, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complications of temporomandibular joint replacement surgery in adult patients: A systematic review and meta-analysis.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2025
Same author

Hyperspectral signals in the soil: Plant-soil hydraulic connection and disequilibrium as mechanisms of drought tolerance and rapid recovery.

Plant, cell & environment·2024
Same author

Eribulin as first-line treatment in older patients with advanced breast cancer: A multicenter phase II trial [SAKK 25/14].

Journal of geriatric oncology·2022
Same author

Predictive risk factors for persistent pain following total prosthetic temporomandibular joint replacement.

The British journal of oral & maxillofacial surgery·2022
Same author

Empirical and Earth system model estimates of boreal nitrogen fixation often differ: A pathway toward reconciliation.

Global change biology·2021
Same author

Streamlining differential exon and 3' UTR usage with diffUTR.

BMC bioinformatics·2021
Same journal

Indications for and strategies to reduce blood transfusion for craniosynostosis surgery: a narrative review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

A case-control study of MRI features in pediatric atypical teratoid rhabdoid tumor and medulloblastoma.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

High-dose chemotherapy with autologous stem cell rescue in children under 5 years of age with central nervous system embryonal tumors: results from a prospective cohort in an upper-middle-income country.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

Advantages of the double-incision approach in endoscopic management of unicoronal synostosis.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

Impact of blood product removal versus temporary cerebrospinal fluid diversion on permanent shunting rates in posthemorrhagic hydrocephalus of prematurity: a comparative meta-analysis.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
Same journal

Ruptured cerebral arteriovenous malformation associated with enlarged parietal foramina: a rare surgical case with pathogenetic implications.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery·2026
See all related articles

Congenital infections pose a significant risk for fetal brain injury and lifelong morbidity. Early screening and diagnosis of maternal infections, including TORCH complex agents, are crucial for timely intervention and improved outcomes.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Neurology
  • Infectious Diseases

Background:

  • Fetal brain injury is a major cause of long-term disability.
  • Infections during pregnancy can lead to fetal brain damage.
  • Screening for congenital infections is vital, especially with risk factors or abnormal ultrasound findings.

Purpose of the Study:

  • To highlight the importance of screening for congenital infections in pregnancy.
  • To outline diagnostic approaches for identifying infectious etiologies of fetal brain injury.

Main Methods:

  • Review of common congenital infections and their impact on fetal brain development.
  • Discussion of antenatal ultrasound findings indicative of brain abnormalities.
  • Emphasis on maternal serologic testing for infectious agents.

Related Experiment Videos

Main Results:

  • Congenital infections, particularly TORCH complex agents (toxoplasmosis, rubella, cytomegalovirus, herpes, varicella), are key contributors to fetal brain injury.
  • The timing of maternal infection in pregnancy significantly influences the risk and severity of fetal damage.
  • Antenatal ultrasound can detect structural brain abnormalities such as hydrocephalus, periventricular leukomalacia, calcifications, and hemorrhage.

Conclusions:

  • Maternal serologic tests are essential for diagnosing infectious causes of fetal brain injury.
  • Screening should include TORCH complex pathogens, parvovirus B19, HIV, and coxsackieviruses.
  • Prompt identification and management of congenital infections can mitigate long-term morbidity in newborns.