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Updated: Aug 8, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Pneumococcal disease and asplenia: the importance of vaccination
S C Clarke1, P Christie, G F Edwards
1Scottish Meningococcus and Pneumococcus Reference Laboratory, Stobhill Hospital, North Glasgow University Hospitals Trust, Glasgow.
Abstract:
Pneumococcal disease is an important cause of morbidity and mortality, particularly in certain patient groups including those who have been splenectomised or have no functioning spleen. Recent deaths in two asplenic patients from pneumococcal disease should remind doctors of the importance of vaccination in asplenic individuals. The current guidelines for vaccination in such patients are highlighted and discussed. The need for a national asplenic register is also suggested.
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Vaccinations
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The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Pneumonia I: Introduction