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Atherosclerosis and secondary deep vein thrombosis: a difficult correlation

F Bilora1, V Boccioletti, F Petrobelli

  • 1Clinica Medica II, Azienda Ospedaliera di Padova, Italy. franca.bilora@sanita.padova.it

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|June 19, 2003
PubMed

Insights

This study found no increased atherosclerosis risk in patients with secondary deep vein thrombosis (DVT). Atherosclerosis markers were similar between DVT patients and controls, suggesting DVT is not a significant risk factor.

Area of Science:

  • Vascular Medicine
  • Cardiovascular Research
  • Thrombosis Studies

Background:

  • Deep vein thrombosis (DVT) is a condition affecting blood circulation.
  • The relationship between DVT and atherosclerosis requires further investigation.
  • Understanding risk factors for atherosclerosis is crucial for cardiovascular health.

Purpose of the Study:

  • To compare the degree of atherosclerosis in patients with secondary DVT versus a matched control group.
  • To evaluate atherosclerosis markers in the carotid arteries, femoral arteries, and abdominal aorta.
  • To determine if secondary DVT is an independent risk factor for atherosclerosis.

Main Methods:

  • Echo color Doppler imaging was used to examine the arterial tree.
  • Computerized methods measured intima-media thickness (IMT).
  • Presence and degree of atherosclerotic plaques were assessed in the carotid and femoral arteries and abdominal aorta.

Main Results:

  • No significant differences in IMT were observed between the DVT group and the control group.
  • The prevalence and severity of atherosclerotic plaques were comparable in both groups.
  • Exclusion of 28 patients due to hyperhomocysteinemia ensured a focused comparison.

Conclusions:

  • Secondary deep vein thrombosis does not appear to be a significant risk factor for atherosclerosis.
  • Atherosclerosis progression is not demonstrably accelerated in individuals with secondary DVT.
  • Further research may explore other potential links or confounding factors.

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