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Weight variance associated with atypical neuroleptics in nursing home dementia patients
1Department of Psychiatry, Brown University, Providence RI 02903, USA.
Objective:
Atypical antipsychotics have been reported to cause significant weight gain. This study examined potential weight gain associated with the use of olanzapine or risperidone.
Design:
A retrospective chart review.
Setting:
Three long-term care facilities.
Participants:
Dementia patients (n = 50) given olanzapine or risperidone for the management of noncognitive behavioral disturbances.
Measurements:
Weight changes over a 4-month period.
Results:
Overall, patients in both groups lost weight over a 4-month period. Four (16%) of the risperidone patients and no olanzapine patients gained more than 5 pounds.
Conclusion:
Weight change does not seem to be a significant clinical issue for older dementia patients taking low doses of atypical neuroleptics.
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